Accurate design of megadalton-scale two-component icosahedral protein complexes
نویسندگان
چکیده
منابع مشابه
Accurate design of megadalton-scale two-component icosahedral protein complexes.
Nature provides many examples of self- and co-assembling protein-based molecular machines, including icosahedral protein cages that serve as scaffolds, enzymes, and compartments for essential biochemical reactions and icosahedral virus capsids, which encapsidate and protect viral genomes and mediate entry into host cells. Inspired by these natural materials, we report the computational design a...
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ژورنال
عنوان ژورنال: Science
سال: 2016
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.aaf8818